The Cubs host the Giants at 7:05, and the White Sox play the Twins at 7:10. The Cardinals have the night off.
The EIU Panthers open the season at home against Western Illinois at 6:00. In Top 25 action, 10th ranked Tennessee hosts Appalachian State, and #23 Louisville plays Charlotte.
Jimmy Garoppolo and the Patriots visit the Giants, the Bears play the Browns, the Colts are in Cincinnati, the Packers battle the Chiefs.
Mattoon at Shelbyville, Tri-County hosts Arcola, Altamont against Casey-Westfield, Arthur-Lovington/Atwood-Hammond plays Villa Grove, Okaw Valley is at Neoga, Cumberland takes on Windsor/Stew-Stras, Effingham heads to Newton, Pana vs. Central A&M, South Central hosts St. Elmo/Brownstown, Tuscola takes on Tolono Unity, and Olney hosts Mount Carmel
Arcola hosts Villa Grove; Casey-Westfield @ Flora; T-town plays Sullivan; Mt. Zion and Altamont are at Tuscola
Mattoon hosts Charleston, Paris and Urbana; Casey-Westfield battles Flora; Shelbyville @ Maroa-Forsyth; Tuscola hosts Altamont and Mt. Zion; Arcola has a triangular with Villa Grove and Oblong; Sullivan hosts T-town
Cumberland takes on Newton, and Olney goes to Lawrenceville