From Illinois State Police:
Update: As of 7:45 p.m. All Lanes are cleared on I-72 at mileposts 181 and I-57 ramps. The scene is clear
Earlier: As of 5:25 p.m. I-72 Westbound is Shutdown from Champaign to Exit 176, you may have to re-enter I-72 West from Route 47. All ramps from Champaign I-57 North and South are blocked off to I-72 west. Please seek an alternate route, a 3 to 4 hour closure is expected.
Earlier: As of 4:30 p.m. ISP are on the scene of a serious personal injury rollover crash on I-72 westbound at milepost 181. Both westbound lanes are blocked at this time. Please seek an alternate route for time being and expect delays.